đź•‘ 16:00 CET / 10:00 EST
đź“… January 26, 2023
đź“Ť Online
Title: Genome graphs: Models, Algorithms, and Applications
Abstract:
Rapid advances in high-throughput sequencing are enabling widespread intra-species sequencing and cataloging population diversity. Graph representations of multiple reference genomes are increasingly being used to capture this genetic diversity and reduce single reference bias. This leads to several interesting questions as to which genomes or variants should be included, and how the resulting graphs can be utilized. Graph genomes also require rethinking traditional bioinformatics tasks such as read mapping. In this talk, I will present my group’s research on variant selection and sequence-to-graph mapping algorithms.
Recorded video: https://youtu.be/Ut9XNTU7-h0